editedbook
Publication: IIP Proceedings Year: 2022, Month: November Page No: 89-97, ISSN/ISBN: 978-93-95632-66-9, DOI/Link: https://www.rsquarel.org/assets/docupload/rsl2023489025BF31BF30A.pdf
QUANTITATIVE STUDY OF BIOLOGICALLY IMPORTANT S-NITROSOTHIOL: CONTRIBUTION OF SIGMA-HOLE INTERACTIONS
Area/Stream: Chemical, Material Sciences & Nano Technology, Authors: Sumit Kumar, Ravindra Kumar Keywords: S-Nitrosothiol, Sigma-Hole, Lewis acid, nitric oxide, coronary artery diseases. Book Name /series: Futuristic Trends in Chemical, Material Sciences & Nano Technology, Volume 2, Book 12, Part 1, Chapter 6Publication: IIP Proceedings Year: 2022, Month: November Page No: 89-97, ISSN/ISBN: 978-93-95632-66-9, DOI/Link: https://www.rsquarel.org/assets/docupload/rsl2023489025BF31BF30A.pdf
Abstract:
Nitric oxide is an important compound for inter and intra cellular signal processing during various physiological conditions and it helps to increase the flow of blood inside human tissues. S-nitrosothiol is the major component during nitric oxide production under biological conditions. The interaction of -SNO group of S-nitrosothiol with amino acids is important in biological context. The interaction can occur through two σ-holes/ chalcogen bonding formed close to Sulphur along S-N and S-C bonding. Some relevant examples show here that ionic state of -SNO group plays a pivotal role during this interaction. Ionized and neutral Lewis bases with S-nitrosothiol through σ-hole/ chalcogen bonding along S-N bonding forms more stable complex than that along S-C bonding.
Cite this: Sumit Kumar, Ravindra Kumar,"QUANTITATIVE STUDY OF BIOLOGICALLY IMPORTANT S-NITROSOTHIOL: CONTRIBUTION OF SIGMA-HOLE INTERACTIONS", Futuristic Trends in Chemical, Material Sciences & Nano Technology, Volume 2, Book 12, Part 1, Chapter 6, November, 2022, 89-97, 978-93-95632-66-9, https://www.rsquarel.org/assets/docupload/rsl2023489025BF31BF30A.pdf
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