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Publication: IIP Proceedings Year: 2022, Month: November Page No: 147-158, ISSN/ISBN: 978-93-95632-87-4 , DOI/Link: https://rsquarel.org/assets/docupload/rsl202338A171C170658BA.pdf
PRO-DRUG DEVELOPMENT
Area/Stream: Pharmacy & Nursing, Authors: Nitin Solanki, Ravindra Mishra, M Harsha Rathore, Himanshi Bhalerao, Radharaman Tiwari, Keywords: Pro-drug, pharmacokinetic, biopharmaceutical. Book Name /series: Futuristic Trends in Pharmacy & Nursing ,Volume 2, Book 25, Part 1, Chapter 13Publication: IIP Proceedings Year: 2022, Month: November Page No: 147-158, ISSN/ISBN: 978-93-95632-87-4 , DOI/Link: https://rsquarel.org/assets/docupload/rsl202338A171C170658BA.pdf
Abstract:
Pro-drug plays a very essential role in the field of pharmaceutical drug discovery and development, by improving the pharmacokinetic, biopharmaceutical property of the medicinally active agent and produce the desired therapeutic effect at the site of action. The term pro-drug is defined as the derivative of the active drug molecules which are biologically inert and produced the pharmacological effect by in-vivo conversion of the enzymatic and chemical. the main aim of the development of pro-drug in pharmaceutical drug discovery and development to overcome some incompatibility that is effective to produce the desired pharmacological effect that is chemical instability, low solubility, pre systematic toxicity, low target selectivity, etc. in this review we have discussed the concept, classification and some examples of the pro-drug which are used to produce the desired pharmacological effect by binding to the targeted site.
Cite this: Nitin Solanki, Ravindra Mishra, M Harsha Rathore, Himanshi Bhalerao, Radharaman Tiwari, ,"PRO-DRUG DEVELOPMENT", Futuristic Trends in Pharmacy & Nursing ,Volume 2, Book 25, Part 1, Chapter 13, November, 2022, 147-158, 978-93-95632-87-4 , https://rsquarel.org/assets/docupload/rsl202338A171C170658BA.pdf
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