editedbook
Publication: IIP Proceedings Year: 2022, Month: November Page No: 57-66, ISSN/ISBN: 978-93-95632-87-4, DOI/Link: https://rsquarel.org/assets/docupload/rsl2023A466A2598232D00.pdf
FLOATING MICROSPHERES A NEW TREND IN THE DELIVERY OF GASTRO RETENTIVE MEDICATIONS
Area/Stream: Pharmacy & Nursing, Authors: A. Rajesh Pavan, Gorantla Naresh Babu, Dr. S.B.Thirumalesh Naik Keywords: Floating microspheres, GRDDS, FDDS. GRT Book Name /series: Futuristic Trends in Pharmacy & Nursing ,Volume 2, Book 25, Part 1, Chapter 5Publication: IIP Proceedings Year: 2022, Month: November Page No: 57-66, ISSN/ISBN: 978-93-95632-87-4, DOI/Link: https://rsquarel.org/assets/docupload/rsl2023A466A2598232D00.pdf
Abstract:
There is no control over the delivery of conventional dose forms. Gastric resident time and gastric emptying are two crucial parameters that have a substantial impact on the drug's ability to treat certain conditions, and it produces differences in the drug's retention period. Drug levels in plasma change depending on the dosing type. As a result, among all gastro-retentive medication administration methods, the floating microsphere is one of the most dependable and creative methods to solve these issues. Due to their extreme appropriateness for targeting, floating microspheres are primarily gaining relevance. The main reason floating microspheres are becoming more and more popular is because of how well-suited they are for delivering medications to the stomach, dispersing them evenly over the gastric fluid to prevent variations in gastric emptying, and increasing drug release. Additionally, this technique greatly facilitates the development of oral formulations with controlled and delayed releases fostering changes in the pharmaceutical sector. The anatomy and physiology stomach, intestines, and components govern the retentive medication delivery method, according to the current review. This review's objective is to shed light on the latest literature regarding the value of Microspheres that float in new medication delivery systems, Formulation techniques, classification, and recent scientific developments in the formulations of floating microspheres using various drug classes.
Cite this: A. Rajesh Pavan, Gorantla Naresh Babu, Dr. S.B.Thirumalesh Naik,"FLOATING MICROSPHERES A NEW TREND IN THE DELIVERY OF GASTRO RETENTIVE MEDICATIONS", Futuristic Trends in Pharmacy & Nursing ,Volume 2, Book 25, Part 1, Chapter 5, November, 2022, 57-66, 978-93-95632-87-4, https://rsquarel.org/assets/docupload/rsl2023A466A2598232D00.pdf
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