editedbook
Publication: IIP Proceedings Year: 2022, Month: November Page No: 229-234, ISSN/ISBN: 978-93-95632-86-7 0, DOI/Link: https://rsquarel.org/assets/docupload/rsl20232F2CDD7451DA17B.pdf
EVALUATION OF ANTI-ULCER ACTIVITIES OF ETHANOLIC EXTRACT OF PARMOTREMA PRAESOREDIOSUM
Area/Stream: Pharmacy & Nursing, Authors: S. Lahari, L. Pranathi, G. MadhaviLatha, M. Ummer Keywords: Parmotrema praesorediosum, Permeliaceae, Lichens, anti-ulcer activity, acid neutralizing capacity, neutralise acids and Gastric hydrogen potassium ATPase inhibitory, ethanol extract. Book Name /series: Futuristic Trends in Pharmacy & Nursing, Volume 2, Book 23, Chapter 18Publication: IIP Proceedings Year: 2022, Month: November Page No: 229-234, ISSN/ISBN: 978-93-95632-86-7 0, DOI/Link: https://rsquarel.org/assets/docupload/rsl20232F2CDD7451DA17B.pdf
Abstract:
Traditional medicine has traditionally used plants as a therapeutic source to treat both human and animal ailments. Plants are the source of a variety of important secondary metabolites with pharmacological and pharmacognostic consequences that have the potential to become future "super medicines." The biotic and abiotic stressors that affect the in-vivo production of these metabolites lead to a constant accumulation of various phytochemicals and their derivatives, which can be helpful in designing and developing potential medications in the future. The Permeliaceae plant Parmotrema praesorediosum is a rich source of phytochemicals with therapeutic value, including lichen acid, tannins, saponins, flavonoids, terpenoids, alkaloids, and sterols. The current project goal is to evaluate the lichen Parmotrema praesorediosum anti-ulcer properties.In this study, we evaluated the anti-ulcer activity of the ethanol extract and the ability of the invitro approach to neutralise acids and Gastric hydrogen potassium ATPase inhibitory movement in stomach . The extract significantly reduced the neutralise acids to 11.75 at the 1000 mg concentration compared to 15.8 for standard aluminum hydroxide + magnesium hydroxide (500 mg). During Gastric hydrogen potassium ATPase inhibitory movement, the extract showed a maximum inhibition rate of 62% at 100 μg compared to 69% for standard omeprazole. This study indicates, the ethanol extract contains several compounds with antiulcer activity and can therefore be used as an alternative medicine for the disease.
Cite this: S. Lahari, L. Pranathi, G. MadhaviLatha, M. Ummer,"EVALUATION OF ANTI-ULCER ACTIVITIES OF ETHANOLIC EXTRACT OF PARMOTREMA PRAESOREDIOSUM", Futuristic Trends in Pharmacy & Nursing, Volume 2, Book 23, Chapter 18, November, 2022, 229-234, 978-93-95632-86-7 0, https://rsquarel.org/assets/docupload/rsl20232F2CDD7451DA17B.pdf
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