editedbook

INSULIN: A CENTENARIAN DRUG: PAST, PRESENT AND FUTURE TRENDS

Area/Stream: Medical Sciences,
Authors: Dr. Sushrut Ingawale (MD, DNB),Dr. Tanvi Borse (MBBS),Dr. Shiamak Cooper (MBBS),
Keywords: diabetes mellitus, insulin, glucose-responsive, ultra-fast, technosphere, thermo-stable.
Book Name /series: Futuristic Trends in Medical Science, Volume 2, Book 22, Part 3, Chapter 3
Publication: IIP Proceedings

Year: 2022,
Month: November

Page No: 204-212,
ISSN/ISBN: 978-93-95632-96-6,
DOI/Link: https://rsquarel.org/assets/docupload/rsl2023B320D44E44E6654.pdf


Abstract:

Diabetes Mellitus (DM) is a major lifestyle disease, with over 460 million patients in the world. Its effects on the human body and its progression have contributed to higher morbidity, mortality and healthcare resource utilization. History is replete with evidence of the devastating effects of DM. This led to immense research and development in understanding the disease better and finding it a suitable cure. The year 2021 marks a century to the discovery of the medical marvel-Insulin, that revolutionized the treatment of diabetes. Over these years, there have been constant efforts to mitigate the adverse effects related to insulin administration and to improve the ease of administration. The bothersome effects of insulin causing weight gain and hypoglycemia have shown to be a hurdle in its usage. These not only cause worsening of the disease process but also prove to be factors in patient compliance. Yet, the benefits have outweighed the adverse events. With the advent of molecular biotechnology, came the ability to alter the configuration of insulin and similar molecules. This along with increased grants in the field of insulin research led to the ongoing development of newer forms of insulin such as – glucose responsive insulin, oral insulins, thermostable insulin, once-weekly dosing insulin, inhaled insulin, etc. The future years hold major ground for redefining the place of insulin in the treatment of diabetes.

Cite this: Dr. Sushrut Ingawale (MD, DNB),Dr. Tanvi Borse (MBBS),Dr. Shiamak Cooper (MBBS),,"INSULIN: A CENTENARIAN DRUG: PAST, PRESENT AND FUTURE TRENDS", Futuristic Trends in Medical Science, Volume 2, Book 22, Part 3, Chapter 3, November, 2022, 204-212, 978-93-95632-96-6, https://rsquarel.org/assets/docupload/rsl2023B320D44E44E6654.pdf
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