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Publication: IIP Proceedings Year: 2022, Month: November Page No: 127-156, ISSN/ISBN: 978-93-95632-92-8, DOI/Link: https://rsquarel.org/assets/docupload/rsl2023F996610F85055CF.pdf
THE POWER OF BLACK PEPPER (PIPER NIGRUM) IN AYURVEDA
Area/Stream: Medical Sciences, Authors: Dr. Uma Maheswari, Sreeshma. M. K Keywords: Black pepper, piperine, phytochemistry, anticancer activity, antioxidant activity, ancient ayurveda Book Name /series: Futuristic Trends in Medical Sciences,Volume 2, Book 21, Part 2, Chapter 1Publication: IIP Proceedings Year: 2022, Month: November Page No: 127-156, ISSN/ISBN: 978-93-95632-92-8, DOI/Link: https://rsquarel.org/assets/docupload/rsl2023F996610F85055CF.pdf
Abstract:
The field of ayurveda medicine offers potential zero-side-effect remedies to a wide range of issues we often face. Black pepper unquestionably holds a special place in ayurveda medicine, and frequent use can help you reap a host of health advantages. The "King of spices," black pepper (Piper nigrum L.), is a popular spice that gives food its unique flavour while also enhancing the flavour of other ingredients. Indepth research has also been done on the biological characteristics and phytoactive components of Piper nigrum. However, an updated collection of these data is not yet available to give a comprehensive profile of P. nigrum's therapeutic properties. This work aims to conduct a thorough assessment of the scientific literature on the pharmacological qualities, phytochemical makeup, and traditional usage of P. nigrum. Using a combination of keywords, information was found using reputable electronic databases (e.g., Science Direct and Google Scholar). Additionally, Google was used. The literature search was limited to English-language sources, including books and internet content. Both in human and veterinary medicine, India had the longest history of P. nigrum cases., particularly for gastrointestinal problems in animals and menstruation and ear-nose-throat illnesses in people. The majority of the ingredients were seeds and fruits, and the main methods of preparation were powder, pills or tablets, and paste. Additionally, it was discovered that Piper nigrum and its bioactive components possessed significant pharmacological characteristics. Biofilm, bacterial efflux pumps, bacterial swarming, and swimming motilities were all inhibited, which resulted in antimicrobial efficacy against a variety of pathogens. Studies have demonstrated that it has antioxidant capabilities against a variety of reactive oxygen and nitrogen species, including the scavenging of superoxide anion, hydrogen peroxide, nitric oxide, DPPH, and ABTS. It also has a loweringeffect on ferric and molybdenum. It has also been found that antioxidant enzymes can be improved in vivo. Piper nigrum also showed anticancer activity against a variety of cell lines from the breast, colon, cervical, and prostate by several mechanisms such as cytotoxicity, apoptosis, autophagy, and signalling pathway interference. Its anti-diabetic efficacy has also been confirmed in vivo, as has its hypolipidemic activity, as evidenced by a drop in cholesterol, triglycerides, and low-density lipoprotein levels and an increase in high-density lipoprotein. Piper nigrum has antiinflammatory, analgesic, anticonvulsant, and neuroprotective properties as well. Piperine is the most abundant bioactive ingredient found in P.nigrum, however other substances such as piperic acid, piperlonguminine, pellitorine, piperolein B, piperamide, piperettine, and (-)- kusunokinin were also discovered. As a final note, P. nigrum is not only the "King of Spices," but also a member of the kingdom of medicinal agents, containing a plethora of bioactive chemicals with potential nutraceutical and pharmaceutical applications.
Cite this: Dr. Uma Maheswari, Sreeshma. M. K,"THE POWER OF BLACK PEPPER (PIPER NIGRUM) IN AYURVEDA", Futuristic Trends in Medical Sciences,Volume 2, Book 21, Part 2, Chapter 1, November, 2022, 127-156, 978-93-95632-92-8, https://rsquarel.org/assets/docupload/rsl2023F996610F85055CF.pdf
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