editedbook
Publication: IIP Proceedings Year: 2022, Month: November Page No: 1-15, ISSN/ISBN: 978-93-95632-92-8, DOI/Link: https://rsquarel.org/assets/docupload/rsl2023C7A3990A2E6002A.pdf
PSYCHOBIOTICS: THE NEXT GENERATION ADJUVANT THERAPY AND ITS REVOLUTIONARY CONTRIBUTION IN TREATMENT FOR PARKINSON’S DISEASE.
Area/Stream: Medical Sciences, Authors: Nishi Jayesh Patel, Dr. Murtaza Hajoori, Dr. Piyush Desai Keywords: Parkinson’s Disease, Psychobiotics, dysbiosis, gut-brain-axis, gut-interference Book Name /series: Futuristic Trends in Medical Sciences,Volume 2, Book 21, Part 1, Chapter 1Publication: IIP Proceedings Year: 2022, Month: November Page No: 1-15, ISSN/ISBN: 978-93-95632-92-8, DOI/Link: https://rsquarel.org/assets/docupload/rsl2023C7A3990A2E6002A.pdf
Abstract:
Parkinson’s Disease is a Neurodegenerative disorder. In prevalence Parkinson’s Disease ranks second following Alzheimer’s disease. Parkinson is not curable but treatment revolves around controlling the symptoms. Most preferrable approach is medicating with Levodopa drug, with time the drug dosage goes on increasing until reaches the highest level as gradually the drug keeps on decreasing its effectiveness besides it manifests multiple side effects within the patient’s body. Doctors would last resort to surgery favourably deep brain stimulation that would reduce the drug dosage to certain level however effectiveness is only 30% to 60%. Substantial concern with the drug treatment is its conversion to dopamine within the gut itself before it reaches the brain and only 1 to 10% of dopamine gets available to the brain due this gut interference hence bioavailability of dopamine decreases and the doses keep on increasing unnecessarily. In order to overcome these concerns Psychobiotics serve as the most approachable adjuvant therapy. Psychobiotics are a set of probiotics that are used to treat neurodegenerative and neuronal disorders and nervous conditions. Psychobiotics exerts their effect directly by establishing in the gut and indirectly by sending signals via the gut-brainaxis. Particularly for Parkinson’s disease it helps to lengthen the course of medication by preventing interference with drug treatment thus decreasing adaptability and controls the major side effects of the primary levodopa drug therapy used to treat Parkinson’s disease. Overall increase the quality of life for Parkinson’s patients especially for the ones with an early age disease onset.
Cite this: Nishi Jayesh Patel, Dr. Murtaza Hajoori, Dr. Piyush Desai,"PSYCHOBIOTICS: THE NEXT GENERATION ADJUVANT THERAPY AND ITS REVOLUTIONARY CONTRIBUTION IN TREATMENT FOR PARKINSON’S DISEASE.", Futuristic Trends in Medical Sciences,Volume 2, Book 21, Part 1, Chapter 1, November, 2022, 1-15, 978-93-95632-92-8, https://rsquarel.org/assets/docupload/rsl2023C7A3990A2E6002A.pdf
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